The new body-horror movie "The Substance" is a wild time, It also took co-stars Demi Moore and Margaret Qualley way out of their comfort zones.

Starring alongside Demi Moore is Margaret Qualley, as the women play two sides of the same aerobics instructor. Moore is a recently fired 50-year-old named Elisabeth Sparkle, who begins injecting herself with a serum to create a younger,

The Substance overflows with brilliant, disgusting, and hilarious body horror. The Substance is an awesome accomplishment of design, from the clinical-yet-do-it-yourself instructions of the titular procedure,

It's not long before Demi and her doppelganger are at each other's throats. Complications ensue when Sue is hired by Elisabeth's old boss (Quaid is scarily hilarious as Harvey) to star in a new workout show called "Pump It Up.

The actress stars alongside Margaret Qualley and Dennis Quaid in Coralie Fargeat’s gleefully grotesque movie about an aging celebrity who takes an experimental drug that gives her a younger self.

Coralie Fargeat’s sci-fi shocker follows the downward spiral of a 50-year-old movie star who resorts to drastic measures

The provocative new film “The Substance,” about an aging celebrity (Demi Moore) who takes an illicit drug to be young again, opened on September 20 following its May premiere in competition at the Cannes Film Festival,

The body horror nightmare story is sensual, unhinged, grotesque, and will have you howling with laughter. Demi Moore has never been better.