After a whole lot of news about a whole lot of nothing, the San Francisco 49ers finally reached an extension agreement with receiver Brandon Aiyuk. The fourth-year receiver who ranked seventh in ...

Rams 0-2. Series record: 49ers lead 78-69-3. Last meeting: Rams beat 49ers 21-20 in Santa Clara, Calif. on Jan. 7. Last week: 49ers lost to Minnesota 23-17; Rams lost to Arizona 41-10. 49ers offense: ...

Given that the calf strain to 49ers running back Christian McCaffrey suddenly and unexpectedly became an Achilles tendon, too, on the team’s first injury report of the year, 49ers fans were nervous ...

The San Francisco 49ers are trying to do the near-impossible: go from Super Bowl runners-up to Super Bowl champions. Though the 1970 Dallas Cowboys, 1971 Miami Dolphins, and 2017 New England ...

SANTA CLARA, Calif. (AP) — San Francisco 49ers safety Talanoa Hufanga was a full participant in practice for the first time since tearing a ligament in his knee last November and could be set to ...

LATEST Sept. 14, 10:30 a.m. The San Francisco 49ers are placing Christian McCaffrey on injured reserve on Saturday, according to multiple reports. ESPN’s Adam Schefter and NFL Network’s Ian ...

The season isn't over for the 49ers despite their upset loss to the Vikings. In fact, there is a benefit to it. Here is how. Losing to the Minnesota Vikings was pitiful for the San Francisco 49ers.

The San Francisco 49ers didn't need Christian McCaffrey, a historic day from Brock Purdy, or a defensive shutout to prove to the rest of the league that a hangover will not exist in 2024.

Minnesota Vikings wide receiver Justin Jefferson suffered an apparent leg injury in the second half of his team's Week 2 game against the San Francisco 49ers. Jefferson was banged-up while ...

Jefferson caught it in stride just across midfield after it soared 55 yards in the air and ran diagonally toward the 49ers sideline, before stutter-stepping at the 32 and veering the opposite ...